Antengene
RESEARCH FIELD

R&D and Innovation

Candidate Molecule

Target/
Mechanism

Rights

Preclinical

IND

Phase I

Phase II

Phase Ⅲ

NDA

Marketing

Candidate Molecule

Target/
Mechanism

Rights

Preclinical

IND

Phase I

Phase II

Phase Ⅲ

NDA

Marketing

  • PD-L1
  • Worldwide
  • Pan-cancer (>15 solid tumors including CRC, GC) with MSI-H/dMMR, mono, single-arm, ORR, 2L/3L

  • BTC, combo with chemo vs. chemo, randomized, OS, 1L

  • SC, mono, single-arm, ORR, 2L

  • NSCLC, combo, 1L

  • NSCLC, combo, 2L

  • GC, combo, 1L/2L

  • TMB-H, mono, single-arm, 2L/3L

  • EC, single-arm, combo with lenvatinib, 2L

  • HCC, combo with VEGF inhibitor, 1L/2L

  • RCC, combo with VEGF inhibitor, 1L/2L

  • WT1
  • Greater China
  • Multiple indications

  • AML、MPM、OC、UC

  • GAS6/AXL
  • Greater China
  • NSCLC/OC/Kidney cancer/Pancreatic cancer

  • OC/Kidney cancer/Bladder cancer

  • COX-2 + EP-4
  • Greater China
  • Cancer pain/Chronic pain

  • FGFR1/2/3
  • Worldwide
  • BTC/mUC

  • PSMA+
    targeted TKI
  • Worldwide
  • HCC/Prostate cancer

  • IO therapy for
    multiple
    indications
  • Greater China
  • Multiple indications

  • Next generation
    IO therapy
  • Worldwide
  • Multiple indications

  • Heptavalent
    version of
    3D189
  • Greater China
  • Multiple indications

  • Not disclosed
  • Worldwide
  • Multiple indications

  • Not disclosed
  • Worldwide
  • Multiple indications

  1. KN035
  2. 3D189
  3. 3D229
  4. 3D1001+3D1002
  5. 3D185
  6. 3D011
  7. 3D197
  8. 3D057
  9. 3D059
  10. 3D060
  11. 3D062